As of 2019, Ajani Charles has been a journalist for Thrive Global, a behaviour change technology and media organization to support individuals struggling with stress and burnout.

Operation Prefrontal Cortex was co-founded by renowned filmmaker Julien Christian Lutz, professionally known as Director X, and his longtime friend Danell Adams after Lutz’s experience as a victim of public gun violence in Toronto, and it is a program harnessing the power of mindfulness and meditation to help reduce the incidents of gun violence, mass violence, and police violence in Toronto.

Project Healthy Minds is a new millennial/Gen Z-driven non-profit startup focused on tackling one of the defining issues of the 21st century: the growing mental health crisis.

Ajani Charles has worked with Calm as an ambassador and producer, writing articles on behalf of the company, promoting the many mental health benefits of Calm’s platform to his audience, producing photographs for the company and being featured in the platform’s Calm Stories series.

Mindfulness And Other Crucial Skills I Never Learned In High School is a workshop by Ajani Charles, initially designed for high school students throughout the Toronto District School Board. 

Ajani Charles has worked as a mentor through CAMH: The Centre For Addiction And Mental Health, Canada’s largest mental health institution, since 2017.

In 2021, Ajani Charles launched a series of meditation playlists via Spotify to provide his audience with easily-accessible audio for mindfulness meditations.